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Is It Legal to Buy 1S-LSD Online in Europe? A Country-by-Country Breakdown

November 4, 2025

As interest in psychedelics and legal research chemicals grows, one question is increasingly asked across laboratories and research circles: Is it legal to buy 1S-LSD online in Europe? This guide explores the legality of 1S-LSD, a novel analog of LSD, across several European countries—offering researchers and institutions clear, up-to-date information on what’s permitted and what’s not.

What Is 1S-LSD?

1S-LSD is a lysergamide compound structurally related to LSD-25, featuring a trimethylsilyl modification that allows it to bypass certain national drug laws. Like other analogs (e.g., 1P-LSD, 1D-LSD), it acts as a prodrug of LSD, likely converting into LSD-25 after ingestion. However, it is marketed strictly for scientific and analytical purposes.

Unlike LSD-25—which is listed as a controlled substance in nearly all countries—1S-LSD remains legal in some jurisdictions, making it an attractive option for legitimate researchers.

Legal Status of 1S-LSD in Key European Countries

Here’s a breakdown of how legal LSD analogs like 1S-LSD are viewed across the European Union and beyond:

🇩🇪 Germany

✅ Legal for research

As of October 2025, 1S-LSD is not scheduled under the BtMG or NpSG, meaning it remains legal to buy, sell, and possess for non-human research. However, its status may change quickly, as previous analogs (like 1D-LSD) were banned in 2024.

🇦🇹 Austria

⚠️ Grey area

While 1S-LSD is not explicitly banned, Austrian analog laws may apply. Researchers are advised to consult legal experts and ensure the substance is used only in a scientific context.

🇨🇿 Czech Republic

✅ Permissive stance

The Czech Republic is known for its liberal research policies. While LSD itself is banned, 1S-LSD is not scheduled, making it legal for research.

🇳🇱 Netherlands

⚠️ Unclear

While the Netherlands has strict controls on LSD and psilocybin, 1S-LSD is not explicitly listed. However, analog laws may still apply depending on interpretation.

🇫🇷 France

❌ Illegal

France maintains strict analog laws. 1S-LSD, due to its structural similarity to LSD-25, is likely considered illegal under current legislation.

🇮🇹 Italy

❌ Likely banned

Italy enforces broad analog laws. While 1S-LSD is not directly named, it may be treated as an LSD analog, making its possession or sale illegal.

🇵🇱 Poland

⚠️ Legal uncertainty

1S-LSD is not scheduled, but researchers should exercise caution. Polish authorities have acted swiftly in banning similar analogs.

🇪🇸 Spain

✅ Permitted for research

Spain allows possession of unscheduled compounds for non-human research. 1S-LSD falls under this category and is therefore legal for scientific use.

🇸🇮 Slovenia

✅ Legal for research use

In Slovenia, 1S-LSD is not listed as a controlled substance. Labs and academic institutions can legally order 1S-LSD for authorized research.

Summary: Can You Legally Buy 1S-LSD Online in the EU?

CountryLegal Status for Research Use
Germany✅ Legal
Austria⚠️ Grey Area
Czech Republic✅ Legal
Netherlands⚠️ Unclear
France❌ Likely Illegal
Italy❌ Likely Illegal
Poland⚠️ Uncertain
Spain✅ Legal
Slovenia✅ Legal

🧪 Disclaimer: This article is for informational purposes only and does not constitute legal advice. Always consult local authorities before ordering or using research chemicals.

1S-LSD offers researchers a legal LSD alternative in countries where traditional psychedelics are strictly controlled. While its legality varies from country to country, in many European nations it remains accessible for non-human, scientific research.

If you’re planning to buy 1S-LSD online in the EU, ensure that your vendor is reputable, provides lab-tested materials, and operates in full legal compliance.

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